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1

Formamide and the origin of life

Raffaele Saladino, Claudia Crestini, Samanta Pino, Giovanna Costanzo, Ernesto Di Mauro

Journal:

Physics of Life Reviews

Year:

2012

Language:

english

File:

PDF, 1008 KB

english, 2012

2

Kaledo, a board game for nutrition education of children and adolescents at school: cluster randomized controlled trial of healthy lifestyle promotion

Viggiano, Alessandro, Viggiano, Emanuela, Di Costanzo, Anna, Viggiano, Andrea, Andreozzi, Eleonora, Romano, Vincenzo, Rianna, Ines, Vicidomini, Claudia, Gargano, Giuliana, Incarnato, Lucia, Fevola, Ce

Journal:

European Journal of Pediatrics

Year:

2015

Language:

english

File:

PDF, 858 KB

english, 2015

3

Healthy lifestyle promotion in primary schools through the board game Kaledo: a pilot cluster randomized trial

Viggiano, Emanuela, Viggiano, Alessandro, Di Costanzo, Anna, Viggiano, Adela, Viggiano, Andrea, Andreozzi, Eleonora, Romano, Vincenzo, Vicidomini, Claudia, Di Tuoro, Daniela, Gargano, Giuliana, Incarn

Journal:

European Journal of Pediatrics

Year:

2018

Language:

english

File:

PDF, 367 KB

english, 2018

4

Formamide Chemistry and the Origin of Informational Polymers

Raffaele Saladino, Claudia Crestini, Fabiana Ciciriello, Giovanna Costanzo, Ernesto Di Mauro

Journal:

Chemistry & Biodiversity

Year:

2007

Language:

english

File:

PDF, 278 KB

english, 2007

5

Synthesis and Degradation of Nucleobases and Nucleic Acids by Formamide in the Presence of Montmorillonites

Raffaele Saladino, Claudia Crestini, Umberto Ciambecchini, Fabiana Ciciriello, Giovanna Costanzo, Ernesto Di Mauro

Journal:

Year:

2004

Language:

english

File:

PDF, 224 KB

english, 2004

6

Origin of Informational Polymers: The Concurrent Roles of Formamide and Phosphates

Raffaele Saladino, Claudia Crestini, Veronica Neri, Fabiana Ciciriello, Giovanna Costanzo, Ernesto Di Mauro

Journal:

Year:

2006

Language:

english

File:

PDF, 319 KB

english, 2006

7

Formamide in non-life/life transition

Raffaele Saladino, Claudia Crestini, Samanta Pino, Giovanna Costanzo, Ernesto Di Mauro

Journal:

Physics of Life Reviews

Year:

2012

Language:

english

File:

PDF, 79 KB

english, 2012

8

Role of mitochondrial uncoupling protein 2 in cancer cell resistance to gemcitabine

Elisa Dalla Pozza, Claudia Fiorini, Ilaria Dando, Marta Menegazzi, Anna Sgarbossa, Chiara Costanzo, Marta Palmieri, Massimo Donadelli

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2012

Language:

english

File:

PDF, 727 KB

english, 2012

9

A case of savant syndrome in a child with autism spectrum disorder

Finocchiaro, Maria, Di Blasi, Francesco Domenico, Zuccarello, Rosa, Costanzo, Angela Antonia, Cantagallo, Claudia, Amata, Maria Teresa, Zingale, Marinella, Elia, Maurizio

Journal:

International Journal on Disability and Human Development

Year:

2015

Language:

english

File:

PDF, 513 KB

english, 2015

10

A garden for ideoscopy

Costanzo, Claudia González

Journal:

Year:

2002

Language:

english

File:

PDF, 100 KB

english, 2002

11

The management of the domestic refrigeration: microbiological status and temperature

Vegara, Alberto, Rita Festino, Anna, Di Ciccio, Pierluigi, Costanzo, Claudia, Pennisi, Luca, Ianieri, Adriana

Journal:

British Food Journal

Year:

2014

Language:

english

File:

PDF, 261 KB

english, 2014

12

The safety of atezolizumab plus chemotherapy for the treatment of metastatic lung cancer

Manzo, Anna, Carillio, Guido, Montanino, Agnese, Sforza, Vincenzo, Palumbo, Giuliano, Esposito, Giovanna, Costanzo, Raffaele, Sandomenico, Claudia, La Manna, Carmine, Martucci, Nicola, La Rocca, Anton

Journal:

Expert Opinion on Drug Safety

Year:

2020

File:

PDF, 684 KB

2020

13

Retinoic acid-induced differentiation in a human neuroblastoma cell line is associated with an increase in nitric oxide synthesis

Dario Ghigo, Claudia Priotto, Daria Migliorino, Daniela Geromin, Cristina Franchino, Roberta Todde, Costanzo Costamagna, Gianpiero Pescarmona, Amalia Bosia

Journal:

Journal of Cellular Physiology

Year:

1998

Language:

english

File:

PDF, 203 KB

english, 1998

14

One-Pot TiO2-Catalyzed Synthesis of Nucleic Bases and Acyclonucleosides from Formamide: Implications for the Origin of Life

Raffaele Saladino, Umberto Ciambecchini, Claudia Crestini, Giovanna Costanzo, Rodolfo Negri, Ernesto Di Mauro

Journal:

Year:

2003

Language:

english

File:

PDF, 200 KB

english, 2003

15

Cover Picture: Synthesis and Degradation of Nucleobases and Nucleic Acids by Formamide in the Presence of Montmorillonites (ChemBioChem 11/2004)

Raffaele Saladino, Claudia Crestini, Umberto Ciambecchini, Fabiana Ciciriello, Giovanna Costanzo, Ernesto Di Mauro

Journal:

Year:

2004

File:

PDF, 24 KB

2004

16

Synthesis and Degradation of Nucleic Acid Components by Formamide and Cosmic Dust Analogues

Raffaele Saladino, Claudia Crestini, Veronica Neri, John R. Brucato, Luigi Colangeli, Fabiana Ciciriello, Ernesto Di Mauro, Giovanna Costanzo

Journal:

Year:

2005

Language:

english

File:

PDF, 158 KB

english, 2005

17

Synthesis and Degradation of Nucleobases and Nucleic Acids by Formamide in the Presence of Montmorillonites

Raffaele Saladino, Claudia Crestini, Umberto Ciambecchini, Fabiana Ciciriello, Giovanna Costanzo, Ernesto Di Mauro

Journal:

Year:

2005

File:

PDF, 23 KB

2005

18

Functional analysis of MLH1 mutations linked to hereditary nonpolyposis colon cancer

Minna Nyström-Lahti, Claudia Perrera, Markus Räschle, Elena Panyushkina-Seiler, Giancarlo Marra, Anna Curci, Barbara Quaresima, Francesco Costanzo, Michele D'Urso, Salvatore Venuta, Josef Jiricny

Journal:

Genes, Chromosomes and Cancer

Year:

2002

Language:

english

File:

PDF, 192 KB

english, 2002

19

Insight into 2-phenylpyrazolo[1,5-a]pyrimidin-3-yl acetamides as peripheral benzodiazepine receptor ligands: Synthesis, biological evaluation and 3D-QSAR investigation

Silvia Selleri, Paola Gratteri, Camilla Costagli, Claudia Bonaccini, Annarella Costanzo, Fabrizio Melani, Gabriella Guerrini, Giovanna Ciciani, Barbara Costa, Francesca Spinetti, Claudia Martini, Fabr

Journal:

Bioorganic & Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 1.20 MB

english, 2005

20

Benzodiazepine receptor ligands. 8: Synthesis and pharmacological evaluation of new pyrazolo[5,1-c] [1,2,4]benzotriazine 5-oxide 3- and 8-disubstituted: High affinity ligands endowed with inverse-agonist pharmacological efficacy

Gabriella Guerrini, Annarella Costanzo, Giovanna Ciciani, Fabrizio Bruni, Silvia Selleri, Camilla Costagli, François Besnard, Barbara Costa, Claudia Martini, Gaetano De Siena, Petra Malmberg-Aiello

Journal:

Bioorganic & Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 315 KB

english, 2006

21

Novel 3-iodo-8-ethoxypyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide as promising lead for design of α5-inverse agonist useful tools for therapy of mnemonic damage

Gabriella Guerrini, Giovanna Ciciani, Giovanni Cambi, Fabrizio Bruni, Silvia Selleri, François Besnard, Marina Montali, Claudia Martini, Carla Ghelardini, Nicoletta Galeotti, Annarella Costanzo

Journal:

Bioorganic & Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 293 KB

english, 2007

22

Novel 3-aroylpyrazolo[5,1-c][1,2,4]benzotriazine 5-oxides 8-substituted, ligands at GABAA/benzodiazepine receptor complex: Synthesis, pharmacological and molecular modeling studies

Gabriella Guerrini, Giovanna Ciciani, Giovanni Cambi, Fabrizio Bruni, Silvia Selleri, Fabrizio Melani, Marina Montali, Claudia Martini, Carla Ghelardini, Monica Norcini, Annarella Costanzo

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 1.41 MB

english, 2008

23

New 3-, 8-disubstituted pyrazolo[5,1-c][1,2,4]benzotriazines useful for studying the interaction with the HBp-3 area (hydrogen bond point area) in the benzodiazepine site on the γ-aminobutyric acid type A (GABAA) receptor

Gabriella Guerrini, Giovanna Ciciani, Fabrizio Bruni, Silvia Selleri, Fabrizio Melani, Simona Daniele, Claudia Martini, Annarella Costanzo

Journal:

Bioorganic & Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 1.17 MB

english, 2011

24

A possible prebiotic synthesis of purine, adenine, cytosine, and 4(3H)-pyrimidinone from formamide: implications for the origin of life

Raffaele Saladino, Claudia Crestini, Giovanna Costanzo, Rodolfo Negri, Ernesto Di Mauro

Journal:

Bioorganic & Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 108 KB

english, 2001

25

2-Arylpyrazolo[1,5-a]pyrimidin-3-yl acetamides. New potent and selective peripheral benzodiazepine receptor ligands

Silvia Selleri, Fabrizio Bruni, Camilla Costagli, Annarella Costanzo, Gabriella Guerrini, Giovanna Ciciani, Barbara Costa, Claudia Martini

Journal:

Bioorganic & Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 305 KB

english, 2001

26

Mechanism of degradation of 2′-deoxycytidine by formamide: Implications for chemical DNA sequencing procedures

Raffaele Saladino, Claudia Crestini, Enrico Mincione, Giovanna Costanzo, Ernesto Di Mauro, Rodolfo Negri

Journal:

Bioorganic & Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 734 KB

english, 1997

27

Synthesis and BZR affinity of pyrazolo[1,5-a]pyrimidine derivatives. part 1: study of the structural features for BZR recognition

Silvia Selleri, Fabrizio Bruni, Camilla Costagli, Annarella Costanzo, Gabriella Guerrini, Giovanna Ciciani, Barbara Costa, Claudia Martini

Journal:

Bioorganic & Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 618 KB

english, 1999

28

The Role of the Formamide/Zirconia System in the Synthesis of Nucleobases and Biogenic Carboxylic Acid Derivatives

Raffaele Saladino, Veronica Neri, Claudia Crestini, Giovanna Costanzo, Michele Graciotti, Ernesto Di Mauro

Journal:

Journal of Molecular Evolution

Year:

2010

Language:

english

File:

PDF, 428 KB

english, 2010

29

About a Formamide-Based Origin of Informational Polymers: Syntheses of Nucleobases and Favourable Thermodynamic Niches for Early Polymers

Raffaele Saladino, Claudia Crestini, Fabiana Ciciriello, Giovanna Costanzo, Ernesto Di Mauro

Journal:

Origins of Life and Evolution of Biospheres

Year:

2006

Language:

english

File:

PDF, 246 KB

english, 2006

30

Benzodiazepine receptor ligands — Part II. Synthesis and biological evaluation of pyrazolo[5,1-c][1,2,4]benzotriazine 4-oxide

Annarella Costanzo, Gabriella Guerrini, Fabrizio Bruni, Giovanna Ciciani, Silvia Selleri, Silvia Cappelletti, Barbara Costa, Claudia Martini, Antonio Lucacchini

Journal:

European Journal of Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 603 KB

english, 1998

31

Anp32e/Cpd1 regulates protein phosphatase 2A activity at synapses during synaptogenesis

Roxana V. Costanzo, Guillermo J. Vilá-Ortíz, Claudia Perandones, Héctor Carminatti, Antoni Matilla, Martín Radrizzani

Journal:

European Journal of Neuroscience

Year:

2006

Language:

english

File:

PDF, 2.25 MB

english, 2006

32

Modulation of guinea-pig cardiac L-type calcium current by nitric oxide synthase inhibitors

Maria Pia Gallo, Dario Ghigo, Amalia Bosia, Giuseppe Alloatti, Costanzo Costamagna, Claudia Penna, Renzo C. Levi

Journal:

The Journal of Physiology

Year:

1998

Language:

english

File:

PDF, 1011 KB

english, 1998

33

Tipin/Tim1/And1 protein complex promotes Polα chromatin binding and sister chromatid cohesion

Errico, Alessia, Cosentino, Claudia, Rivera, Teresa, Losada, Ana, Schwob, Etienne, Hunt, Tim, Costanzo, Vincenzo

Journal:

The EMBO Journal

Year:

2009

Language:

english

File:

PDF, 1.31 MB

english, 2009

34

ATM activates the pentose phosphate pathway promoting anti-oxidant defence and DNA repair

Cosentino, Claudia, Grieco, Domenico, Costanzo, Vincenzo

Journal:

The EMBO Journal

Year:

2010

Language:

english

File:

PDF, 705 KB

english, 2010

35

GEMC1 is a TopBP1-interacting protein required for chromosomal DNA replication

Balestrini, Alessia, Cosentino, Claudia, Errico, Alessia, Garner, Elizabeth, Costanzo, Vincenzo

Journal:

Nature Cell Biology

Year:

2010

Language:

english

File:

PDF, 1.78 MB

english, 2010

36

Synthesis of derivatives of pyrazolo[1,5-a]pyrrolo[1,2-c][1,3,6]-benzotriazocine, a new class of compounds with potential CNS activity

Annarella Costanzo, Fabrizio Bruni, Gabriella Guerrini, Silvia Selleri, Petra Malmberg Aiello, Claudia Lamberti

Journal:

Journal of Heterocyclic Chemistry

Year:

1992

File:

PDF, 468 KB

1992

37

Development of ligands at γ-aminobutyrric acid type A (GABAA) receptor subtype as new agents for pain relief

Gabriella Guerrini, Giovanna Ciciani, Fabrizio Bruni, Silvia Selleri, Claudia Martini, Simona Daniele, Carla Ghelardini, Lorenzo Di Cesare Mannelli, Annarella Costanzo

Journal:

Bioorganic & Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 780 KB

english, 2011

38

The most severe forms of type I autoimmune hepatitis are associated with genetically determined levels of TGF-β1

Natalia Paladino, Ana Claudia Flores, Hugo Fainboim, Teresa Schroder, Miriam Cuarterolo, Carol Lezama, Esteban Gonzáles Ballerga, Diana Levi, Hugo Tanno, Gabriel Costanzo, Lourdes Arruvito, Leonardo F

Journal:

Clinical Immunology

Year:

2010

Language:

english

File:

PDF, 258 KB

english, 2010

39

Formamide as the main building block in the origin of nucleic acids

Giovanna Costanzo, Raffaele Saladino, Claudia Crestini, Fabiana Ciciriello, Ernesto Di Mauro

Journal:

BMC Evolutionary Biology

Year:

2007

Language:

english

File:

PDF, 287 KB

english, 2007

40

Correlation between synaptogenesis and the PTEN phosphatase expression in dendrites during postnatal brain development

Claudia Perandones, Roxana Verónica Costanzo, Valeria Kowaljow, Omar Hilario Pivetta, Hector Carminatti, Martı́n Radrizzani

Journal:

Molecular Brain Research

Year:

2004

Language:

english

File:

PDF, 1.22 MB

english, 2004

41

From formamide to RNA: the roles of formamide and water in the evolution of chemical information

Raffaele Saladino, Claudia Crestini, Fabiana Ciciriello, Samanta Pino, Giovanna Costanzo, Ernesto Di Mauro

Journal:

Research in Microbiology

Year:

2009

Language:

english

File:

PDF, 362 KB

english, 2009

42

Intracellular expression of cytokines in peripheral blood from patients with atherosclerosis before and after carotid endarterectomy

Elisabetta Profumo, Claudia Esposito, Brigitta Buttari, Maria Elena Tosti, Elena Ortona, Paola Margutti, Alessandra Siracusano, Angela Sposato, Alessandro Costanzo, Raffaele Capoano, Bruno Salvati, Ra

Journal:

Atherosclerosis

Year:

2007

Language:

english

File:

PDF, 360 KB

english, 2007

43

Could Interferon Still Play a Role in Metastatic Renal Cell Carcinoma? A Randomized Study of Two Schedules of Sorafenib Plus Interferon-Alpha 2a (RAPSODY)

Sergio Bracarda, Camillo Porta, Corrado Boni, Armando Santoro, Claudia Mucciarini, Antonio Pazzola, Enrico Cortesi, Donatello Gasparro, Roberto Labianca, Francesco Di Costanzo, Alfredo Falcone, Michel

Journal:

European Urology

Year:

2013

Language:

english

File:

PDF, 282 KB

english, 2013

44

Synthesis of novel cognition enhancers with pyrazolo[5,1-c][1,2,4]benzotriazine core acting at γ-aminobutyric acid type A (GABAA) receptor

Guerrini, Gabriella, Ciciani, Giovanna, Costanzo, Annarella, Daniele, Simona, Martini, Claudia, Ghelardini, Carla, Di Cesare Mannelli, Lorenzo, Ciattini, Samuele

Journal:

Bioorganic & Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 708 KB

english, 2013

45

Liposome-Encapsulated Doxorubicin Reverses Drug Resistance by Inhibiting P-Glycoprotein in Human Cancer Cells

Riganti, Chiara, Voena, Claudia, Kopecka, Joanna, Corsetto, Paola Antonia, Montorfano, Gigliola, Enrico, Emanuele, Costamagna, Costanzo, Rizzo, Angela Maria, Ghigo, Dario, Bosia, Amalia

Journal:

Molecular Pharmaceutics

Year:

2011

Language:

english

File:

PDF, 3.89 MB

english, 2011

46

Autophagy induced by p53-reactivating molecules protects pancreatic cancer cells from apoptosis

Fiorini, Claudia, Menegazzi, Marta, Padroni, Chiara, Dando, Ilaria, Dalla Pozza, Elisa, Gregorelli, Alex, Costanzo, Chiara, Palmieri, Marta, Donadelli, Massimo

Journal:

Year:

2013

Language:

english

File:

PDF, 544 KB

english, 2013

47

UCP2 inhibition triggers ROS-dependent nuclear translocation of GAPDH and autophagic cell death in pancreatic adenocarcinoma cells

Dando, Ilaria, Fiorini, Claudia, Pozza, Elisa Dalla, Padroni, Chiara, Costanzo, Chiara, Palmieri, Marta, Donadelli, Massimo

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2013

Language:

english

File:

PDF, 610 KB

english, 2013

48

Cetuximab in non-small-cell lung cancer

Carillio, Guido, Montanino, Agnese, Costanzo, Raffaele, Sandomenico, Claudia, Piccirillo, Maria Carmela, Di Maio, Massimo, Daniele, Gennaro, Giordano, Pasqualina, Bryce, Jane, Normanno, Nicola, Rocco,

Journal:

Expert Review of Anticancer Therapy

Year:

2012

Language:

english

File:

PDF, 504 KB

english, 2012

49

Advanced non-small-cell lung cancer with epidermal growth factor receptor mutations: current evidence and future perspectives

Costanzo, Raffaele, Montanino, Agnese, Di Maio, Massimo, Piccirillo, Maria Carmela, Sandomenico, Claudia, Giordano, Pasqualina, Daniele, Gennaro, Franco, Renato, Perrone, Francesco, Rocco, Gaetano, No

Journal:

Expert Review of Anticancer Therapy

Year:

2013

Language:

english

File:

PDF, 315 KB

english, 2013

50

Treatment of small cell lung cancer

Morabito, Alessandro, Carillio, Guido, Daniele, Gennaro, Piccirillo, Maria Carmela, Montanino, Agnese, Costanzo, Raffaele, Sandomenico, Claudia, Giordano, Pasqualina, Normanno, Nicola, Perrone, France

Journal:

Critical Reviews in Oncology/Hematology

Year:

2014

Language:

english

File:

PDF, 1.21 MB

english, 2014

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